 |
Synthesis and antimicrobial activity of quinoline-based 2-pyrazolines
Munawar, Munawar A., Azad, Muhammad, Athar, Makshoof and Groundwater, Paul W. Synthesis and antimicrobial activity of quinoline-based 2-pyrazolines Chemical Papers, Vol.62, No. 3, 2008, 288-293
|
|
|
Document type:
|
Článok z časopisu / Journal Article |
|
Collection:
|
Chemical papers
|
|
| Author(s) |
Munawar, Munawar A.
Azad, Muhammad
Athar, Makshoof
Groundwater, Paul W.
|
| Title |
Synthesis and antimicrobial activity of quinoline-based 2-pyrazolines
|
| Journal name |
Chemical Papers
|
| Publication date |
2008
|
| Year available |
2008
|
| Volume number |
62
|
| Issue number |
3
|
| ISSN |
0366-6352
|
| Start page |
288
|
| End page |
293
|
| Place of publication |
Poland
|
| Publisher |
Versita
|
| Collection year |
2008
|
| Language |
english
|
| Subject |
270000 Biological Sciences
270100 Biochemistry and Cell Biology
|
| Abstract/Summary |
A series of 2-pyrazolines was prepared in a reaction of quinolinylchalcones with phenyl hydrazine under both conventional and microwave-induced heating. Structures of the synthesized compounds were characterized by spectroscopic data and CHN analyses. All prepared compounds were tested for antimicrobial activity against bacterial strains, viz. Staphylococcus aureus, Salmonella typhii, Escherichia coli, and Shigella dysentery. Almost all synthesized compounds have shown antimicrobial activity; however, compounds with a chloro group as a substituent have been found to be more effective.
|
|
|
