Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interes

Hammam, A. S., Youssef, M. S. K., Atta, F. M. and Mohamed, Th. A. Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interes Chemical Papers, Vol.61, No. 4, 2007, 292-299

Document type: ńĆl√°nok z ńćasopisu / Journal Article
Collection: Chemical papers  

Author(s) Hammam, A. S.
Youssef, M. S. K.
Atta, F. M.
Mohamed, Th. A.
Title Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interes
Journal name Chemical Papers
Publication date 2007
Year available 2007
Volume number 61
Issue number 4
ISSN 0366-6352
Start page 292
End page 299
Place of publication Poland
Publisher Versita
Collection year 2007
Language english
Subject 270000 Biological Sciences
270100 Biochemistry and Cell Biology
Abstract/Summary Tetrabromo-p-benzoquinone reacted with excess aromatic amines to give 2,5-dirylamino-3,6-dibromo-p-benzoquinones. The latter molecules on heating with sodium sulfide in alcohol in the presence of air gave triphenodithiazinediones. Heating with copper powder in nitrobenzene transformed these compounds into the respective indolocarbazolediones. Comparative antimicrobial and antifungal activities of the studied compounds were determined and discussed.
 
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