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Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interes
Hammam, A. S., Youssef, M. S. K., Atta, F. M. and Mohamed, Th. A. Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interes Chemical Papers, Vol.61, No. 4, 2007, 292-299
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Document type:
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Článok z časopisu / Journal Article |
Collection:
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Chemical papers
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Author(s) |
Hammam, A. S. Youssef, M. S. K. Atta, F. M. Mohamed, Th. A.
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Title |
Synthesis of new triphenodithiazine- and indolocarbazolediones of biological interes
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Journal name |
Chemical Papers
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Publication date |
2007
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Year available |
2007
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Volume number |
61
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Issue number |
4
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ISSN |
0366-6352
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Start page |
292
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End page |
299
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Place of publication |
Poland
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Publisher |
Versita
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Collection year |
2007
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Language |
english
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Subject |
270000 Biological Sciences 270100 Biochemistry and Cell Biology
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Abstract/Summary |
Tetrabromo-p-benzoquinone reacted with excess aromatic amines to give 2,5-dirylamino-3,6-dibromo-p-benzoquinones. The latter molecules on heating with sodium sulfide in alcohol in the presence of air gave triphenodithiazinediones. Heating with copper powder in nitrobenzene transformed these compounds into the respective indolocarbazolediones. Comparative antimicrobial and antifungal activities of the studied compounds were determined and discussed.
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