Intracellular Changes of GABA metabolism in Trichoderma viride and other fungi with age and carbon source

Kaliňák, Michal, Liptaj, Tibor, Prónayová, Nadežda and Varečka, Ľudovít Intracellular Changes of GABA metabolism in Trichoderma viride and other fungi with age and carbon source Acta Chimica Slovaca, Vol.1, No. 1, 2008, 134-142

Document type: Článok z časopisu / Journal Article
Collection: Acta Chimica Slovaca  
 
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Author(s) Kaliňák, Michal
Liptaj, Tibor
Prónayová, Nadežda
Varečka, Ľudovít
Title Intracellular Changes of GABA metabolism in Trichoderma viride and other fungi with age and carbon source
Journal name Acta Chimica Slovaca
Publication date 2008
Year available 2008
Volume number 1
Issue number 1
ISBN 978-80-227-2957-4
Start page 134
End page 142
Total pages 9
Place of publication Bratislava
Publisher Slovak Technical University
Collection year 2008
Language english
Subject 270000 Biological Sciences
270100 Biochemistry and Cell Biology
Abstract/Summary The concentration of γ-aminobutyric acid (GABA) in extracts of Trichoderma viride grown on sucrose decreased in an age-dependent manner. GABA also disappeared from mycelium when fungus was transferred to the medium with non-saccharide substrate (citrate). Comparative studies with mycelia of Penicillium simplicissimum and Aspergillus nidulans demonstrated similar development of GABA levels during the cultivation. However, in yeast Saccharomyces cerevisiae the amount of GABA was undetectable under aerobic conditions. Results show that GABA shunt is not only active in filamentous fungi but that it seems to be developmentally regulated.
Keyword(s) filamentous fungi
metabolites
GABA
development
aging
 
 
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