An amperometric sensor for uric acid based on ordered mesoporous carbon-modified pyrolytic graphite electrode

Ma, Yonggen, Hu, Guangzhi, Shao, Shijun and Guo, Yong An amperometric sensor for uric acid based on ordered mesoporous carbon-modified pyrolytic graphite electrode Chemical Papers, Vol.63, No. 6, 2009, 641-645

Document type: Článok z časopisu / Journal Article
Collection: Chemical papers  

Author(s) Ma, Yonggen
Hu, Guangzhi
Shao, Shijun
Guo, Yong
Title An amperometric sensor for uric acid based on ordered mesoporous carbon-modified pyrolytic graphite electrode
Journal name Chemical Papers
Publication date 2009
Year available 2009
Volume number 63
Issue number 6
ISSN 0366-6352
Start page 641
End page 645
Place of publication Poland
Publisher Versita
Collection year 2009
Language english
Subject 250000 Chemical Sciences
Abstract/Summary A novel amperometric sensor for uric acid based on ordered mesoporous carbon modified pyrolytic graphite electrode was developed. Uric acid oxidation was easily catalyzed by this electrode in a phosphate buffer solution at pH 7.0, with an anodic potential decrease about 140 mV compared to bare pyrolytic graphite electrode. The uric acid level was determined by the amperometric method, at a constant potential of 0.31 mV, the catalytic current of uric acid vs. its concentration showed a good linearity in the range of 1.0 × 10−6−1.0 × 10−4 mol L−1, with a correlation coefficient of 0.999. The detection limit was 4.0 × 10−7 mol L−1. The proposed method could be effectively used for uric acid amperometric sensing in human urine.
 
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