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Synthesis of new quinoxalinophenazinediones and tetrahydrobenzodipyrrolotetrones of biological interest
Hammam, Ahmed S., Youssef, Mohamed S. K., Atta, Ferial M. and Mohamed, Thana A. Synthesis of new quinoxalinophenazinediones and tetrahydrobenzodipyrrolotetrones of biological interest Chemical Papers, Vol.62, No. 2, 2008, 194-206
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Author(s) |
Hammam, Ahmed S.
Youssef, Mohamed S. K.
Atta, Ferial M.
Mohamed, Thana A.
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| Title |
Synthesis of new quinoxalinophenazinediones and tetrahydrobenzodipyrrolotetrones of biological interest
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| Journal name |
Chemical Papers
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| Publication date |
2008
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| Year available |
2008
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| Volume number |
62
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| Issue number |
2
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| ISSN |
0366-6352
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| Start page |
194
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| End page |
206
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2008
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| Language |
english
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| Subject |
250000 Chemical Sciences
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| Abstract/Summary |
The reaction of two equivalents of sodium azide with diarylaminodibromo-p-benzoquinone (I) in DMF for 15–24 h produced quinoxalinophenazinediones together with a byproduct identified as diarylaminodiaminobenzoquinone. On the other hand, the reaction of bromanil with active methylenes, such as diethyl malonate and ethyl acetoacetate, resulted in disubstitution products which, on treatment with primary amines, cyclized into benzodipyrroletetrones. Comparative antifungal and antibacterial studies were made.
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