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Three-component, one-pot synthesis of 3,4-dihydropyrimidin-2-(1 H )-ones catalyzed by bromodimethylsulfonium bromide
Shaabani, A. and Maleki, A. Three-component, one-pot synthesis of 3,4-dihydropyrimidin-2-(1 H )-ones catalyzed by bromodimethylsulfonium bromide Chemical Papers, Vol.61, No. 4, 2007, 333-336
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Author(s) |
Shaabani, A.
Maleki, A.
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| Title |
Three-component, one-pot synthesis of 3,4-dihydropyrimidin-2-(1 H )-ones catalyzed by bromodimethylsulfonium bromide
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| Journal name |
Chemical Papers
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| Publication date |
2007
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| Year available |
2007
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| Volume number |
61
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| Issue number |
4
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| ISSN |
0366-6352
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| Start page |
333
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| End page |
336
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2007
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| Language |
english
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| Subject |
250000 Chemical Sciences
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| Abstract/Summary |
An efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-one derivatives by one-pot three-component condensation reaction between an alkyl or aryl aldehyde, a 1,3-dicarbonyl compound, and urea or thiourea in the presence of catalytic amount of bromodimethylsulfonium bromide has been developed. The condensation product was obtained in excellent yields in refluxing ethanol and easily separated from the reaction mixture and purified.
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