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Step by step towards understanding gold glyconanoparticles as elements of the nanoworld
Sihelníková, L. and Tvaroška, I. Step by step towards understanding gold glyconanoparticles as elements of the nanoworld Chemical Papers, Vol.61, No. 4, 2007, 237-255
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Author(s) |
Sihelníková, L.
Tvaroška, I.
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| Title |
Step by step towards understanding gold glyconanoparticles as elements of the nanoworld
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| Journal name |
Chemical Papers
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| Publication date |
2007
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| Year available |
2007
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| Volume number |
61
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| Issue number |
4
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| ISSN |
0366-6352
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| Start page |
237
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| End page |
255
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2007
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| Language |
english
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| Subject |
250000 Chemical Sciences
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| Abstract/Summary |
Gold glyconanoparticles as elements of the nanoworld belong to a group of particles with diameters not exceeding 100 nm. This size scale makes them conformable to common biomolecules. A gold glyconanoparticle consists of three different parts: the gold core, the linkers, and saccharide ligands. The glycocalyx-like surface of these particles mimics the presentation of carbohydrate epitopes of cell surface glycoconjugates. As a consequence, gold glyconanoparticles provide inimitable tools for probing and manipulating the mechanisms of biological processes based on carbohydrate interactions. Each component of the gold glyconanoparticle has a profound effect on the nanoparticle’s properties. Therefore, in this review, elucidation of the overall behavior and properties of gold glyconanoparticles is based on a step by step (component by component) description of the system.
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