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New substituted mono-and bis(imidazolyl)pyridines and their application in nitroaldolisation reaction
Keder, R., Drabina, P., Hanusek, J. and Sedlák, M. New substituted mono-and bis(imidazolyl)pyridines and their application in nitroaldolisation reaction Chemical Papers, Vol.60, No. 4, 2006, 324-326
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Author(s) |
Keder, R.
Drabina, P.
Hanusek, J.
Sedlák, M.
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| Title |
New substituted mono-and bis(imidazolyl)pyridines and their application in nitroaldolisation reaction
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| Journal name |
Chemical Papers
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| Publication date |
2006
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| Year available |
2006
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| Volume number |
60
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| Issue number |
4
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| ISSN |
0366-6352
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| Start page |
324
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| End page |
326
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2006
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
New chiral nitrogen ligands based on the substituted mono-and bis(imidazolyl)pyridines have been prepared and characterised. Their complexes with cupric acetate were used as catalysts in the nitroaldolisation reaction. In the case of optically pure complexes of mono(imidazolyl)pyridine, the isolated products were 2-nitro-1-(2-nitrophenyl)ethanols or 2-nitro-1-(4-nitrophenyl)ethanols in overall yields of 49–93 % and with the maximum enantiomeric excess of 15.6 %. The complexes of bis(imidazolyl)pyridine also catalyse the nitroaldol reaction, the yields being 64–90 %, but with zero enantioselective excess.
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