Synthesis, characterization, and biological activities of some transition metal(II) complexes with the thiosemicarbazone derived from 4-[1-(4-methylphenylsulfonyl)-1 H -indol-3-yl]but-3-en-2-one

Qu, J. Q., Sun, G. C., Wang, L. F. and Qu, L. Synthesis, characterization, and biological activities of some transition metal(II) complexes with the thiosemicarbazone derived from 4-[1-(4-methylphenylsulfonyl)-1 H -indol-3-yl]but-3-en-2-one Chemical Papers, Vol.60, No. 3, 2006, 214-219

Document type: ńĆl√°nok z ńćasopisu / Journal Article
Collection: Chemical papers  

Author(s) Qu, J. Q.
Sun, G. C.
Wang, L. F.
Qu, L.
Title Synthesis, characterization, and biological activities of some transition metal(II) complexes with the thiosemicarbazone derived from 4-[1-(4-methylphenylsulfonyl)-1 H -indol-3-yl]but-3-en-2-one
Journal name Chemical Papers
Publication date 2006
Year available 2006
Volume number 60
Issue number 3
ISSN 0366-6352
Start page 214
End page 219
Place of publication Poland
Publisher Versita
Collection year 2006
Language english
Subject 250000 Chemical Sciences
250300 Organic Chemistry
Abstract/Summary A new 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one thiosemicarbazone (HL) was synthesized derived from 4-[1-(4-methylphenylsulfonyl)-1H-indol-3-yl]but-3-en-2-one. Four transition metal(II) complexes of HL have been prepared. Elemental analysis, molar conductivity, IR, UV, 1H NMR spectra, and TG-DTA have been used to characterize these complexes. The complexes have the general formula ML2, where M = Zn, Cu, Co, and Ni. The ligand and its complexes have been studied for their possible biological activity including anti-inflammatory, antibacterial, and antitumour activity in vitro.
 
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