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Furan-containing thiacyanine analogs and their antimicrobial activity
Kortišová, I., Foltínová, P. and Halgaš, J. Furan-containing thiacyanine analogs and their antimicrobial activity Chemical Papers, Vol.60, No. 1, 2006, 52-55
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Author(s) |
Kortišová, I.
Foltínová, P.
Halgaš, J.
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| Title |
Furan-containing thiacyanine analogs and their antimicrobial activity
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| Journal name |
Chemical Papers
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| Publication date |
2006
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| Year available |
2006
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| Volume number |
60
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| Issue number |
1
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| ISSN |
0366-6352
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| Start page |
52
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| End page |
55
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2006
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
Condensation of quaternary 2-methylbenzothiazolium bromides with 5-(dialkylamino)furan-2-carbaldehydes afforded a series of new thiacyanine analogs. The compounds exhibit significant activities against several bacterial, yeast, and mould strains. Derivatives with dipropylamino substituents showed higher inhibitory effects than those with cyclic secondary amino groups. Hence, the biological activity may have been influenced by the lipophilicity of the compounds. The effect on growth and on the plastid system of the unicellular flagellate Euglena gracilis was also studied.
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