Synthesis, spectral description, and lipophilicity parameters determination of phenylcarbamic acid derivatives with integrated N -phenylpiperazine moiety in the structure

Malík, I., Sedlárová, E., Csöllei, J., Andriamainty, F., Kurfürst, P. and Vančo, J. Synthesis, spectral description, and lipophilicity parameters determination of phenylcarbamic acid derivatives with integrated N -phenylpiperazine moiety in the structure Chemical Papers, Vol.60, No. 1, 2006, 42-47

Document type: Článok z časopisu / Journal Article
Collection: Chemical papers  

Author(s) Malík, I.
Sedlárová, E.
Csöllei, J.
Andriamainty, F.
Kurfürst, P.
Vančo, J.
Title Synthesis, spectral description, and lipophilicity parameters determination of phenylcarbamic acid derivatives with integrated N -phenylpiperazine moiety in the structure
Journal name Chemical Papers
Publication date 2006
Year available 2006
Volume number 60
Issue number 1
ISSN 0366-6352
Start page 42
End page 47
Place of publication Poland
Publisher Versita
Collection year 2006
Language english
Subject 250000 Chemical Sciences
250300 Organic Chemistry
Abstract/Summary The phenylcarbamic acid derivatives with N-phenylpiperazine moiety in the molecule have been prepared. The structure has been confirmed by elemental analysis, IR, 1H NMR, and mass spectral data. For the prepared set of the compounds the lipophilicity parameters have been determined. The experimentally obtained lipophilicity parameters have been correlated with theoretical entries obtained by different computer programs based on the neural network and fragmental methods.
 
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