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Synthesis and Cyclization Reactions with Quinolinyl Keto Esters. I. Chemical Reactivity of Quinolinyl beta-Keto Ester and Quinolinyl alpha,beta-Unsaturated Ketones
Ismail, M. M., Othman, E. S. and Mohamed, H. M. Synthesis and Cyclization Reactions with Quinolinyl Keto Esters. I. Chemical Reactivity of Quinolinyl beta-Keto Ester and Quinolinyl alpha,beta-Unsaturated Ketones Chemical Papers, Vol.59, No. 2, 2005, 117-126
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Attached Files |
| Name |
Description |
MIMEType |
Size |
Downloads |
n592a117.pdf
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592a117.pdf |
application/pdf |
526.51KB |
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| Author(s) |
Ismail, M. M.
Othman, E. S.
Mohamed, H. M.
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| Title |
Synthesis and Cyclization Reactions with Quinolinyl Keto Esters. I. Chemical Reactivity of Quinolinyl beta-Keto Ester and Quinolinyl alpha,beta-Unsaturated Ketones
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| Journal name |
Chemical Papers
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| Publication date |
2005
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| Year available |
2005
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| Volume number |
59
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| Issue number |
2
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| ISSN |
0366-6352
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| Start page |
117
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| End page |
126
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2005
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
3-Acetyl-1-ethyl-4-hydroxyquinolin-2(1H)-one and 1-ethyl-4-hydroxyquinolin-2(1H)-one were prepared and subjected to several and different chemical transformations to give novel heterocyclically 3-substituted quinolinone derivatives of expected important biological activity. So the latter compounds were used to obtain β-keto ester and α, β-unsaturated carbonylquinolinones which were used as alternate precursors to produce many new five-membered heterocyclic as pyrazolyl, isoxazolyl as substituents to the quinolinone moiety. Al1 the structures of the new products were identified on the basis of their chemical behaviour, elemental and spectral analyses.
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