Development of the Analytical Method for LC-MS Detection of Unknown Degradation Product of Alprazolam

Hanyšová, L., Grafnetterová, T., Dubovská, M. and Klimeš, J. Development of the Analytical Method for LC-MS Detection of Unknown Degradation Product of Alprazolam Chemical Papers, Vol.59, No. 2, 2005, 99-102

Document type: Článok z časopisu / Journal Article
Collection: Chemical papers  
 
Attached Files
Name Description MIMEType Size Downloads
n592a99.pdf 592a99.pdf application/pdf 213.86KB 0

Author(s) Hanyšová, L.
Grafnetterová, T.
Dubovská, M.
Klimeš, J.
Title Development of the Analytical Method for LC-MS Detection of Unknown Degradation Product of Alprazolam
Journal name Chemical Papers
Publication date 2005
Year available 2005
Volume number 59
Issue number 2
ISSN 0366-6352
Start page 99
End page 102
Place of publication Poland
Publisher Versita
Collection year 2005
Language english
Subject 250000 Chemical Sciences
250300 Organic Chemistry
250302 Biological and Medical Chemistry
Abstract/Summary The stability of alprazolam ms a pure substance and in the tablets was studied. The gradient HPLC chromatographic conditions were described for LC-MS identification of an impurity. Employing this chromatographic method, the stability of alprazolam under conditions of dry and wet heat was observed. The unknown degradation product was identified using MS detection.
 
 
User Comments
 
Access Statistics: 0 Abstract Views, 0 File Downloads Detailed Statistics
Created: Thu, 07 Jan 2010, 12:03:07 CET by Iveta Drtilová . Detailed History