 |
Development of the Analytical Method for LC-MS Detection of Unknown Degradation Product of Alprazolam
Hanyšová, L., Grafnetterová, T., Dubovská, M. and Klimeš, J. Development of the Analytical Method for LC-MS Detection of Unknown Degradation Product of Alprazolam Chemical Papers, Vol.59, No. 2, 2005, 99-102
|
|
|
Document type:
|
Článok z časopisu / Journal Article |
|
Collection:
|
Chemical papers
|
| |
| Attached Files |
| Name |
Description |
MIMEType |
Size |
Downloads |
n592a99.pdf
|
592a99.pdf |
application/pdf |
213.86KB |
0 |
| Author(s) |
Hanyšová, L.
Grafnetterová, T.
Dubovská, M.
Klimeš, J.
|
| Title |
Development of the Analytical Method for LC-MS Detection of Unknown Degradation Product of Alprazolam
|
| Journal name |
Chemical Papers
|
| Publication date |
2005
|
| Year available |
2005
|
| Volume number |
59
|
| Issue number |
2
|
| ISSN |
0366-6352
|
| Start page |
99
|
| End page |
102
|
| Place of publication |
Poland
|
| Publisher |
Versita
|
| Collection year |
2005
|
| Language |
english
|
| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
250302 Biological and Medical Chemistry
|
| Abstract/Summary |
The stability of alprazolam ms a pure substance and in the tablets was studied. The gradient HPLC chromatographic conditions were described for LC-MS identification of an impurity. Employing this chromatographic method, the stability of alprazolam under conditions of dry and wet heat was observed. The unknown degradation product was identified using MS detection.
|
|
|
|
