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Synthesis, Spectral and Toxicological Studies of Complex Zn(II) with Sulfadiazine
Guru, P., Gautam, R. K. and Goutam, M. P. Synthesis, Spectral and Toxicological Studies of Complex Zn(II) with Sulfadiazine Chemical Papers, Vol.58, No. 5, 2004, 341-347
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Attached Files |
| Name |
Description |
MIMEType |
Size |
Downloads |
n585a341.pdf
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585a341.pdf |
application/pdf |
1.03MB |
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| Author(s) |
Guru, P.
Gautam, R. K.
Goutam, M. P.
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| Title |
Synthesis, Spectral and Toxicological Studies of Complex Zn(II) with Sulfadiazine
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| Journal name |
Chemical Papers
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| Publication date |
2004
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| Year available |
2004
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| Volume number |
58
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| Issue number |
5
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| ISSN |
0366-6352
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| Start page |
341
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| End page |
347
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2004
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
The present paper deals with the spectral and toxicological studies of the complex Zn(II) with antibiotic drug sulfadiazine (2-(p-aminobenzenesulfonamido)pyrimidine), a general formula Zn(C10H10N4O2S) ·MoO4· H2O has been suggested for the complex under study. The geometries of the complexes have been proposed on the basis of magnetic moments, electronic and infrared spectral data. Thermogravimetric analyses have been carried out to determine the pattern of their decomposition. The crystal system, lattice parameters, unit cell volume, and number of molecules in it have been determined by X-ray diffraction data. The toxicity of the synthesized complex was also studied on some internal organs of the albino rats like liver, kidney, adrenal gland, and testis.
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