Synthesis, Spectral and Toxicological Studies of Complex Zn(II) with Sulfadiazine

Guru, P., Gautam, R. K. and Goutam, M. P. Synthesis, Spectral and Toxicological Studies of Complex Zn(II) with Sulfadiazine Chemical Papers, Vol.58, No. 5, 2004, 341-347

Document type: Článok z časopisu / Journal Article
Collection: Chemical papers  
 
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Author(s) Guru, P.
Gautam, R. K.
Goutam, M. P.
Title Synthesis, Spectral and Toxicological Studies of Complex Zn(II) with Sulfadiazine
Journal name Chemical Papers
Publication date 2004
Year available 2004
Volume number 58
Issue number 5
ISSN 0366-6352
Start page 341
End page 347
Place of publication Poland
Publisher Versita
Collection year 2004
Language english
Subject 250000 Chemical Sciences
250300 Organic Chemistry
Abstract/Summary The present paper deals with the spectral and toxicological studies of the complex Zn(II) with antibiotic drug sulfadiazine (2-(p-aminobenzenesulfonamido)pyrimidine), a general formula Zn(C10H10N4O2S) ·MoO4· H2O has been suggested for the complex under study. The geometries of the complexes have been proposed on the basis of magnetic moments, electronic and infrared spectral data. Thermogravimetric analyses have been carried out to determine the pattern of their decomposition. The crystal system, lattice parameters, unit cell volume, and number of molecules in it have been determined by X-ray diffraction data. The toxicity of the synthesized complex was also studied on some internal organs of the albino rats like liver, kidney, adrenal gland, and testis.
 
 
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