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Synthesis, Characterization, Antitumour and Antibacterial Activity of Rare Earth Metal(III) Solid Complexes with Tetraiodofluorescein
Qu, J. Q., Wang, L. F., Zhang, X. P., Zhao, H. and Sun, G. C. Synthesis, Characterization, Antitumour and Antibacterial Activity of Rare Earth Metal(III) Solid Complexes with Tetraiodofluorescein Chemical Papers, Vol.56, No. 2, 2002, 113-116
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Author(s) |
Qu, J. Q.
Wang, L. F.
Zhang, X. P.
Zhao, H.
Sun, G. C.
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| Title |
Synthesis, Characterization, Antitumour and Antibacterial Activity of Rare Earth Metal(III) Solid Complexes with Tetraiodofluorescein
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| Journal name |
Chemical Papers
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| Publication date |
2002
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| Year available |
2002
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| Volume number |
56
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| Issue number |
2
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| ISSN |
0366-6352
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| Start page |
113
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| End page |
116
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2002
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
Eight new solid complexes of tetraiodofluorescein (H2L) with rare earth metals have been prepared and characterized by means of elemental analysis, molar conductivity, IR, 1H NMR, XPS, and TGDTA. The general formula for the complexes is M2L3 · nH2O, where L = tetraiodofluorescein (2,7- OH group deprotonated and the lactonic ring opened); M = La, Ce, Pr, Nd, Sm, Eu, Gd or Y; n = 8, 9, 10, 11 or 14. In vitro, H2L and its complexes have been studied for their possible antitumour activity against Hep-2 pharynx cancer cells and their possible antibacterial activity against Shigella flexner F2a, Salmonella typhi H034, and Staphylococcus aureus.
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