Complexes of Tetraiodofluorescein with Some Transition Metals and their Antitumour Activity

Qu, J. Q. and Wang, L. F. Complexes of Tetraiodofluorescein with Some Transition Metals and their Antitumour Activity Chemical Papers, Vol.56, No. 2, 2002, 109-112

Document type: ńĆl√°nok z ńćasopisu / Journal Article
Collection: Chemical papers  

Author(s) Qu, J. Q.
Wang, L. F.
Title Complexes of Tetraiodofluorescein with Some Transition Metals and their Antitumour Activity
Journal name Chemical Papers
Publication date 2002
Year available 2002
Volume number 56
Issue number 2
ISSN 0366-6352
Start page 109
End page 112
Place of publication Poland
Publisher Versita
Collection year 2002
Language english
Subject 250000 Chemical Sciences
250300 Organic Chemistry
Abstract/Summary Cobalt(II), nickel(II), copper(II), and zinc(II) complexes of tetraiodofluorescein (H2L) have been prepared and characterized by means of elemental analysis, molar conductivity, TG-DTA, IR, UV VIS, and 1H NMR spectra. The general formula for the complexes is ML· nH2O where L = tetraiodofluorescein (2,7-OH group deprotonated and the lactonic ring opened); M = Zn, Cu, Co, and Ni; n = 0, 4, 5, and 2. H2L and its complexes have been studied for their possible antitumour activity against Hep-2 pharynx cancer cells in vitro.
 
 
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Created: Mon, 04 Jan 2010, 10:02:33 CET by Jana Taptińćov√° . Detailed History