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Complexes of Tetraiodofluorescein with Some Transition Metals and their Antitumour Activity
Qu, J. Q. and Wang, L. F. Complexes of Tetraiodofluorescein with Some Transition Metals and their Antitumour Activity Chemical Papers, Vol.56, No. 2, 2002, 109-112
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Author(s) |
Qu, J. Q.
Wang, L. F.
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| Title |
Complexes of Tetraiodofluorescein with Some Transition Metals and their Antitumour Activity
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| Journal name |
Chemical Papers
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| Publication date |
2002
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| Year available |
2002
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| Volume number |
56
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| Issue number |
2
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| ISSN |
0366-6352
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| Start page |
109
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| End page |
112
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2002
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
Cobalt(II), nickel(II), copper(II), and zinc(II) complexes of tetraiodofluorescein (H2L) have been prepared and characterized by means of elemental analysis, molar conductivity, TG-DTA, IR, UV VIS, and 1H NMR spectra. The general formula for the complexes is ML· nH2O where L = tetraiodofluorescein (2,7-OH group deprotonated and the lactonic ring opened); M = Zn, Cu, Co, and Ni; n = 0, 4, 5, and 2. H2L and its complexes have been studied for their possible antitumour activity against Hep-2 pharynx cancer cells in vitro.
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