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γ-Oxocarboxylic Acids in Heterocyclic Synthesis IV. Synthesis of Some Pyridazines Containing Phthalyl- and Tosylamino Acids Using Dicyclohexylcarbodiimide as the Condensing Agent
Aly, A. A. and Wasfy, A. A. F. γ-Oxocarboxylic Acids in Heterocyclic Synthesis IV. Synthesis of Some Pyridazines Containing Phthalyl- and Tosylamino Acids Using Dicyclohexylcarbodiimide as the Condensing Agent Chemical Papers, Vol.58, No. 2, 2004, 126-132
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Document type:
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Článok z časopisu / Journal Article |
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Collection:
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Chemical papers
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| Attached Files |
| Name |
Description |
MIMEType |
Size |
Downloads |
n582a126.pdf
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582a126.pdf |
application/pdf |
156.85KB |
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| Author(s) |
Aly, A. A.
Wasfy, A. A. F.
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| Title |
γ-Oxocarboxylic Acids in Heterocyclic Synthesis IV. Synthesis of Some Pyridazines Containing Phthalyl- and Tosylamino Acids Using Dicyclohexylcarbodiimide as the Condensing Agent
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| Journal name |
Chemical Papers
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| Publication date |
2004
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| Year available |
2004
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| Volume number |
58
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| Issue number |
2
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| ISSN |
0366-6352
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| Start page |
126
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| End page |
132
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| Place of publication |
Poland
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| Publisher |
Versita
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| Collection year |
2004
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
3(2H)-Oxo-, 3(2H)-thioxo- or 3-aminopyridazine derivatives were coupled with N-phthalyl- or N-tosylamino acids in one-step room-temperature reaction using N,N-dicyclohexylcarbodiimide as the condensing agent to furnish the corresponding 3-N-(phthalyl- or tosylamino acids) pyridazine derivatives. Hydrazinolysis of the N-phthalyl derivatives in methanol yielded the corresponding unprotected derivatives. The antibacterial activities of the prepared compounds were tested.
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