Dipeptide Enzymatic Synthesis in a Two-Phase Membrane Reactor

Trusek-Holownia, A. and Noworyta, A. Dipeptide Enzymatic Synthesis in a Two-Phase Membrane Reactor Chemical Papers, Vol.54, No. 6b, 2000, 442-447

Document type: Článok z časopisu / Journal Article
Collection: Chemical papers  
 
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Author(s) Trusek-Holownia, A.
Noworyta, A.
Title Dipeptide Enzymatic Synthesis in a Two-Phase Membrane Reactor
Journal name Chemical Papers
Publication date 2000
Year available 2000
Volume number 54
Issue number 6b
ISSN 0366-6352
Start page 442
End page 447
Place of publication Poland
Publisher Versita
Collection year 2000
Language english
Subject 290000 Engineering and Technology
290600 Chemical Engineering
Abstract/Summary The application of a two-phase system in enzymatic synthesis of bitter dipeptide ZAlaPheOMe was studied. Enzymatic conversion was accompanied by the reactant extraction in membrane contactor. Under experimental conditions, reaction kinetics and reactant mass transfer rates were evaluated and the main resistance of process was estimated. The Hatta number was used to the determination of the ratio of diffusion time to the reaction time. It was shown that the process ran in the kinetic region. Owing to a high enzyme activity and stability and the product extraction to organic phase, the substrate conversion degree 0.8 was achieved after 20 h of reaction time.
 
 
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