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Synthesis and Reactions of 2-(4-Oxochromen-3-yl) benzothiazolium and -benzoxazolium Bromides
Gašparová, Renata, Kleštinec, Mário, Koiš, Pavol and Lácová, Margita Synthesis and Reactions of 2-(4-Oxochromen-3-yl) benzothiazolium and -benzoxazolium Bromides Acta Chimica Slovaca, Vol.2, No. 1, 2009, -
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| Attached Files |
| Name |
Description |
MIMEType |
Size |
Downloads |
acs_0032.pdf
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acs_0032.pdf |
application/pdf |
153.79KB |
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| Author(s) |
Gašparová, Renata
Kleštinec, Mário
Koiš, Pavol
Lácová, Margita
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| Title |
Synthesis and Reactions of 2-(4-Oxochromen-3-yl) benzothiazolium and -benzoxazolium Bromides
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| Journal name |
Acta Chimica Slovaca
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| Publication date |
2009
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| Year available |
2009
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| Volume number |
2
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| Issue number |
1
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| ISSN |
1337-978X
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| Place of publication |
Bratislava
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| Publisher |
Slovak Technical University
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| Collection year |
2009
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| Language |
english
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| Subject |
250000 Chemical Sciences
250300 Organic Chemistry
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| Abstract/Summary |
Benzothiazolium and benzoxazolium bromides 4, 5 were synthesized either by one-pot condensation of substituted 4-oxochromene-3-carboxaldehydes 1 with 2-methylbenzothiazole (2a) or 2-methylbenzoxazole (2b) and benzyl bromide or by condensation of 1 with 2- methylbenzothiazolium or 2-methylbenzoxazolium bromides 3 under microwave irradiation or by the classical heating. The advantage of microwave irradiation in comparison with classical reactions was reflected in the significantly reduced reaction time and increased yields. Reactions of resulting benzothiazolium salt 4b with primary and secondary amines led to 2-substituted derivatives 6 or phenylpyrazolo[3,4-b]pyridine 7.
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| Keyword(s) |
benzoxazolium bromides
benzothiazolium bromodes
microwave irradiation
4-oxochromene-3-carboxaldehydes
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